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USP16 decreases the amount of ubH2A. 2 / 2
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"Joo and colleagues showed that Ubp-M deubiquitinates ubH2A within a nucleosome in vitro and that knockdown of Ubp-M increases ubH2A levels in vivo."

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"Supporting our biochemical assays, Usp16 knockout caused a significant increase of ubH2A levels without any apparent effects on H2A levels (XREF_FIG)."