IndraLab
Statements
USP8 is phosphorylated on Y717. 2 / 2
|
2
rlimsp
"As described earlier, USP8 knockdown induced trichoplein degradation and unscheduled ciliogenesis, whereas these phenomena were ameliorated by expression of endogenous level of FLAG-USP8 WT (Fig. 7e, f; 10 ng ml−1 of Dox). In contrast, equal levels of Y717F/Y810F had only a modest effect, suggesting that phosphorylations of Tyr-717 and Tyr-810 are important for trichoplein-mediated inhibition of ciliogenesis."