IndraLab

Statements

reach
"Prof. Masayuki Noguchi’s team identified that SFN specifically binds to ubiquitinated protease 8 (USP8) in lung adenocarcinoma cells, enhancing the stabilization of receptor tyrosine kinases (RTKs), including EGFR and MET, through abnormal regulation of USP8."
37398672
sparser
"The interaction of USP8 and SFN is critical for USP8 to exert its autodeubiquitination function and avoid dephosphorylation by PP1."
38490326
reach
"SFN-USP8 complex deubiquitinates RTKs and facilitates recycling of RTKs to the plasma membrane."
34405018
reach
"Yunjung Kim et al. [ 65 ]showed that USP8 could specially bind to SFN in lung adenocarcinoma cells."
38490326
reach
"The interaction of USP8 and SFN is critical for USP8 to exert its autodeubiquitination function and avoid dephosphorylation by PP1."
38490326
reach
"In vitro, USP8 binds to SFN and they co-localize at the early endosomes in lung adenocarcinoma cells."
29880877
sparser
"Yunjung Kim et al. [ 65 ]showed that USP8 could specially bind to SFN in lung adenocarcinoma cells."
38490326