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TP53 bound to Ser15 and MDM2 activates TP53. 1 / 1

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"By preventing the formation of the p53/MDM2 complex, Ser15 phosphorylation prevents p53 degradation via the ubiquitin–proteasome pathway, increasing p53 stability and levels within lymph node carcinoma of the prostate prostate cancer cells, making it a critical factor in the antitumour process (54)."

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IndraLab

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TP53 bound to Ser15 and MDM2 activates TP53. 1 / 1

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