IndraLab

Statements


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"Indeed, knockdown of USP13 increased glucose uptake and glycolysis, which could be fully reversed by restoration of PTEN, as gauged by lactate production and glucose incorporation assays (XREF_FIG)."

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"Therefore, USP13-KD also decreases glucose oxidation into TCA cycle metabolites."

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"Functional studies demonstrated that overexpression of USP13 suppressed OSCC cell proliferation, glucose uptake and lactate production in vitro and inhibited tumor growth in vivo."