IndraLab

Statements


PI3K inhibits COPS5. 2 / 2
| 2

reach
"We explored a potential connection between PI3K activity and Jab1 and E2F1 target gene induction, and found that E2F1 and Jab1 co-induction of apoptotic target genes can be inhibited by activated PI3K."

reach
"Besides, PI3K and Akt may participate in the regulation of Jab1 and COPS5 by Bcr-Abl since PI3K and Akt inhibitor LY294002 decreases the promoter activity and mRNA level of Jab1 and COPS5."