IndraLab

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"Maximum inhibition by CAPE was observed at concentrations of 25 microg ml (-1) (approximately 88 microM) CAPE prevented H. pylori- and cytokine induced degradation of IkappaB-alpha protein."
16247412
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"Further, p-IkappaB-alpha, an activated (phosphorylated) form of IkappaB-alpha, and IkappaB-beta, inhibitors of NF-kappaB1 & 2, respectively, were decreased by CAPE to about the same degree (i.e., ~ 44% at 20 microM CAPE) (XREF_TABLE)."
21570765
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"Further, p-IkappaB-alpha, an activated (phosphorylated) form of IkappaB-alpha, and IkappaB-beta, inhibitors of NF-kappaB1 & 2, respectively, were decreased by CAPE to about the same degree (i.e., ~ 44% at 20 microM CAPE) (XREF_TABLE), There were no changes observed in the levels of IkappaB-alpha and C-rel proteins."
21570765
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"Some studies have shown that CAPE inhibits NF-kappaB activation not by blocking the degradation of IkBalpha but by suppressing the interaction of NF-kappaB proteins with DNA [XREF_BIBR, XREF_BIBR, XREF_BIBR, XREF_BIBR, XREF_BIBR, XREF_BIBR, XREF_BIBR, XREF_BIBR]."
| PMC
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"It has also been reported that CAPE inhibits NF-kappaB activation not by blocking the degradation of IkappaBalpha but by suppressing the interaction of NF-kappaB proteins with the DNA [14]."
11734336
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"For inhibiting the IKKbeta/IkappaBalpha/NF-kappaB and JNK/AP -1 signal pathway, CAPE clearly diminished the activation of IKKbeta, IkappaBalpha (inhibitory proteins of NF-kappaB), and JNK through phos[MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"
29957360