IndraLab

Statements

USP4 activates TNF. 3 / 4
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"Ubiquitin specific protease 4 (USP4) targets TRAF2 and TRAF6 for deubiquitination and inhibits TNFalpha induced cancer cell migration."
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"Notably, USP4 overexpression antagonized OGD/R-induced IL-1β, IL-6, and TNF-α transcriptional levels (Fig. 3A–C)."
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"As shown in Fig. 2 B, USP4 overexpression significantly promotes cell apoptosis in FaDu cells in responses to TNF-α with CHX."
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