IndraLab

Statements


FN1 activates SDC4. 8 / 9
1 | 6 2

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"Therefore, to examine the role played by Sdc4 in PCP signaling, we investigated whether FN stimulation of Sdc4 facilitates Fzd7 dependent Rac1 activation."

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"Our results demonstrated that neuronal density, neurite length, and neurite branching were lower in the PDMS group and could be further reversed through activating SDC-4 by FN."

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"Our results demonstrated that neuronal density, neurite length, and neurite branching were lower in the PDMS group and could be further reversed through activating SDC-4 by FN."

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"The effects of Sdc4 on RhoA activity after Sdc4 stimulation by fibronectin are summarized in XREF_FIG."

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"In migrating NC cells, the proteoglycan Syndecan-4 (Syn4) is activated by fibronectin."

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"ECM-bound TG2 acts as a co-receptor of FN for integrin-induced cell adhesion and/or as a bridge protein that interacts with and stimulates syndecan-4 in a transamidase-independent way [80] ."

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"MuSCs can adhere to fibronectin through syndecan-4 and the Wnt receptor Frizzled-7 (SDC4 and FZD7) co and receptor complex, which is activated by both WNT7a and fibronectin ligands."

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"We hypothesized that RhoG might also trigger integrin endocytosis upon engagement of syndecan-4 by fibronectin."