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Berberine inhibits CASP1. 13 / 13
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"Berberine inhibits caspase-1 activation via the ERK1 / 2 signaling pathway ."
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"Berberine Inhibits Caspase-1 Activation via ERK1 / 2 Signaling Pathway Next , we used Ac-YYAD-CMK to determine if the inhibitory effect of berberine on EMT is dependent on caspase-1-mediated pathways ."
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"Berberine, a natural isoquinoline alkaloid with antimicrobial ability, has been found to inhibit the growth, migration, and invasion capacity of HCC in vivo and in vitro by inducing caspase-1 and GSDMD-dependent pyroptosis."
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"Berberine, which is a natural isoquinoline alkaloid, has been reported to inhibit the degradation of caspase-1."
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"These are supported by our observations that berberine and rhein inhibits caspase-1 in vitro ."
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"In addition, berberine inhibits the activation of caspase-1 in HMC-1 cells."
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"Based on the studies, berberine has been proven to activate the ERK1/2 & p38 MAPK, caspase-3 and FOXO3a pathways while inhibiting the activation of NF-κB and caspase-1 signalling pathways."
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"These are supported by our observations that berberine and rhein inhibits caspase-1 in vitro ."
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"The results from the tumor tissues were in accordance with the results from Saos-2 and MG-63 osteosarcoma cells (XREF_FIG), which illustrate that berberine attenuates the activation of caspase-1 and IL-1beta signal pathway."
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"Berberine directly inhibits caspase-1 activation via the ERK1/2 signaling pathway in glioma cells, leading to inhibition of the expression of pro-inflammatory cytokines such as IL-1β and IL-18 [114]."
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"The researchers concluded that the low TSLP production is highly associated to the downregulation of NF-κB and caspase-1 pathway in HMC-1 cells by berberine [ 27 , 28 ]."
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"In the same study, in MG-63 cells, the isoquinolide alkaloid berberine inhibited caspase 1, which resulted in decreased IL-1β expression."
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"In the same study, in MG-63 cells, the isoquinolide alkaloid berberine inhibited caspase 1, which resulted in decreased IL-1β expression."
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