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"The results from the tumor tissues were in accordance with the results from Saos-2 and MG-63 osteosarcoma cells (XREF_FIG), which illustrate that berberine attenuates the activation of caspase-1 and IL-1beta signal pathway."

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"Berberine Inhibits Caspase-1 Activation via ERK1 / 2 Signaling Pathway Next , we used Ac-YYAD-CMK to determine if the inhibitory effect of berberine on EMT is dependent on caspase-1-mediated pathways ."

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"Berberine, a natural isoquinoline alkaloid with antimicrobial ability, has been found to inhibit the growth, migration, and invasion capacity of HCC in vivo and in vitro by inducing caspase-1 and GSDMD-dependent pyroptosis."

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"Berberine inhibits caspase-1 activation via the ERK1 / 2 signaling pathway ."