IndraLab

Statements

Barium(2+) inhibits KCNH2. 3 / 3
| 3
reach
"Extracellular barium (Ba 2+ o) block of HERG exhibits strong voltage dependence consistent with a binding site deep in the pore, similar to the site now confirmed crystallographically for KcsA."
12356854
reach
"State dependent barium block of wild-type and inactivation deficient HERG channels in Xenopus oocytes."
10896755
reach
"The HERG like current was blocked by dofetilide (DOF) in a concentration dependent manner (IC (50) = 13 +/- 4 nM, mean +/- SE) and high concentrations of Ba (2+) (1 and 10 mM)."
10712445