IndraLab

Statements


CYLD leads to the deubiquitination of DVL1. 3 / 3
1 | 2

"<span class="match term0">CYLD</span> negatively regulates the Wnt/beta-catenin signaling pathway by deubiquitinating <span class="match term1">Dvl</span> proteins"

reach
"Ubiquitination of Dvl1 was diminished by overexpression of wild-type CYLD and enhanced by overexpression of a catalytically inactive CYLD (CYLD C601S)."

reach
"As shown in Figure 5(d), ectopic expression of CYLD significantly (whereas SPATA2 slightly) reduced ubiquitination of DVL1."