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This Service

A database built with INDRA combining content from numerous readers and databases. This page allows you to curate the loaded statements. For more information please see the manual.

This Project

INDRA is developed by indralabs, a part of the Harvard Medical School Laboratory of Systems Pharmacology.

This project, indra_db, is also developed by the indralab team. For more information on how we procure our sources, you can go here. This work was funded by ARO grant W911NF‐15‐1‐0544 under the DARPA Communicating with Computers program.

IndraLab

Statements

SCN8A increases the amount of CDYL. 2 / 2

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"We next performed ChIP analysis to investigate the molecular mechanism by which CDYL regulates SCN8A transcription."

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"Together, these results support an argument that CDYL inhibits SCN8A transcription mainly through recruiting H3K27me3 methyltransferase activity, possibly also the HDAC activity albeit to a less degree, to the intronic silencer of the gene."

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Our Sources:

INDRA allows us to combine the results from a multitude of sources. In particular, the INDRA Database draws on the following...