IndraLab

Statements


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"Stimulation of Gq coupled receptors was found to inhibit TREK activity by a mechanism involving protein kinase PKC and channel phosphorylation XREF_BIBR, XREF_BIBR, XREF_BIBR."

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"Gq coupled receptor agonists inhibited TREK1 and TREK2 in heterologous expression system, and this effect was observed in bovine adrenal glomerulosa cells."

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"In addition, stimulation of Gq coupled receptors, including metabotropic mGluR1, and mGluR5 receptors, inhibits TREK-1 activity."