IndraLab

Statements

OAZ1 binds USP28. 2 / 2
| 2
reach
"AZ1 binds to USP28 at the Ub-tail binding channel—distal end of the cleft, at the intersection between the thumb, palm, and finger subdomains."
38816515
reach
"AZ1, VSM, and FT206 bind to USP28 at different overlapping positions inside the same hydrophobic cleft, located at the intersection of the USP-thumb and palm subdomains in the center of the concave part of the USP S1-site, which acts as a binding surface for the globular domain of the distal Ub moiety of the cleaved substrate (Figs."
38816515