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This Service

A database built with INDRA combining content from numerous readers and databases. This page allows you to curate the loaded statements. For more information please see the manual.

This Project

INDRA is developed by indralabs, a part of the Harvard Medical School Laboratory of Systems Pharmacology.

This project, indra_db, is also developed by the indralab team. For more information on how we procure our sources, you can go here. This work was funded by ARO grant W911NF‐15‐1‐0544 under the DARPA Communicating with Computers program.

IndraLab

Statements

USP10 activates MYC. 2 / 2

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"To our surprise, SIRT6 gene suppression resulted in a lower level of increase in c-Myc target gene expression than that of USP10 knockdown, implying that additional factors may contribute to USP10 mediated c-Myc suppression."

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"Thus, we determined whether USP10 functions as a tumor suppressor through SIRT6 mediated c-Myc inactivation."

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Our Sources:

INDRA allows us to combine the results from a multitude of sources. In particular, the INDRA Database draws on the following...