IndraLab

Statements


USP4 increases the amount of PKM2. 4 / 4
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"We already found that USP4 can increase PKM2 expression, and the upregulation of PKM2 by USP4 is associated with its enzymatic activity."

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"Because USP4 upregulates PKM2 expression, we speculate that USP4 may increase these gene expressions due to its upregulation of PKM2."

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"Knockdown of USP4 reduces PKM2 levels and results in a reduction in cell proliferation and the glycolysis rate."

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"Second, USP4 increased the level of PKM2 in gastric cancer cells."