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USP1 inhibits Neoplasm Metastasis. 2 / 2

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"Most importantly, pharmacological intervention of USP1 function by pimozide or ML323 significantly represses breast cancer metastasis in mice, suggesting a rationale for using USP1 inhibitors for treatment of patients with breast cancer."

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"A reduction in USP1 levels inhibits cancer cell proliferation, suppresses metastasis, and sensitizes cancer cells to irradiation and chemotherapeutic drugs in various cancers [17,18]."

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USP1 inhibits Neoplasm Metastasis. 2 / 2

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