IndraLab

Statements

KLF4 binds OTUD7B. 11 / 11
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reach
"An immunoprecipitation-mass spectrometry analysis showed that OTUD7B directly binds to KLF4 (Kruppel-like factor 4)."
38084712
sparser
"Therefore, the interaction between OTUD7B and KLF4 was investigated further."
38084712
reach
"Therefore, the interaction between OTUD7B and KLF4 was investigated further."
38084712
sparser
"Series of OTUD7B and KLF4 fragments were constructed to further investigate the binding domains required for interaction between OTUD7B and KLF4."
38084712
sparser
"A region of OTUD7B (amino acid [aa] 151–aa446) and a region of KLF4 (aa200–aa397) were required for OTUD7B to bind to KLF4 (Figure  xref )."
38084712
reach
"Series of OTUD7B and KLF4 fragments were constructed to further investigate the binding domains required for interaction between OTUD7B and KLF4."
38084712
sparser
"In the further study, we utilized co-immunoprecipitation experiments to examine the interaction of OTUD7B with KLF4 and found that KLF4 was co-immunoprecipitated by anti-OTUD7B antibody."
32685020
sparser
"The specificity of their interaction was verified by increased association of OTUD7B with KLF4 in OTUD7B-overexpressed cells (Figure xref G)."
32685020
reach
"As anticipated, co-immunoprecipitation experiments revealed that OTUD7B interacted with and deubiquitylated KLF4."
32685020
sparser
"An immunoprecipitation–mass spectrometry analysis showed that OTUD7B directly binds to KLF4 (Krüppel‐like factor 4)."
38084712
sparser
"These results demonstrate that the OTUD7B‐KLF4 axis is a novel molecular target for CH treatment."
38084712