IndraLab

Statements

USP5 deubiquitinates CACNA1H. 4 / 5
1 | 4
reach
"As reported, overexpression of USP5 decreases ubiquitination of CaV3.2, which in turn decreases channel internalization [64]."
33422652
reach
"Thus, targeting Cav3.2 deubiquitination by USP5 is a potential therapeutic target for pain associated with inflammatory disorders [62]."
35740277
reach
"Knockdown of USP5 via shRNA increases Cav3.2 ubiquitination, decreases Cav3.2 protein levels, and reduces Cav3.2 whole-cell currents."
25189210
reach
"Deubiquitination of Cav3.2 by USP5 promotes channel stability and function, thus mediating the development of neuropathic and inflammatory pain in rodents [7]."
38001892