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This Service

A database built with INDRA combining content from numerous readers and databases. This page allows you to curate the loaded statements. For more information please see the manual.

This Project

INDRA is developed by indralabs, a part of the Harvard Medical School Laboratory of Systems Pharmacology.

This project, indra_db, is also developed by the indralab team. For more information on how we procure our sources, you can go here. This work was funded by ARO grant W911NF‐15‐1‐0544 under the DARPA Communicating with Computers program.

IndraLab

Statements

Chelator inhibits PSMD14. 2 / 2

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"Ovaa et al. reported a mono-Ub probe (Fig. 13e) with a zinc chelator 8-mercaptoquinoline (8-MQ) linked to the C terminus of Ub.129 Inhibition assays showed that the probe can inhibit Rpn11/Rpn8 with an IC50 value about 2 μM."

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"Thiolutin ( 42 ), a disulfide-containing antibiotic and anti-angiogenic compound produced by Streptomyces, was reported to function as a zinc chelator that inhibits RPN11 and other JAMM metalloproteases [ xref ]."

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Our Sources:

INDRA allows us to combine the results from a multitude of sources. In particular, the INDRA Database draws on the following...