IndraLab

Statements

reach
"USP22 facilitated EPI-induced breast cancer progression and metastasis by enhancing adipose triglyceride lipase (ATGL)-mediated lipolysis."
39151008
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"This study has defined a USP22-mediated lipolysis circuit that links the chronic stress–induced EPI production to breast cancer pathogenesis through the AKT-USP22-FOXO1-ATGL pathway."
39151008
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"In addition to lactate and glucose metabolism, we show here that EPI promotes breast cancer metastasis through a USP22-mediated lipolysis circuit."
39151008
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"Future studies integrated with a psychologist team are needed to address this critical question.Our study revealed that USP22-mediated lipolysis circuit links the chronic stress–induced EPI production to breast cancer pathogenesis through the AKT-USP22-FOXO1-ATGL pathway across a wide range of human breast cancers, irrespective of their HER expression status."
39151008
reach
"Epinephrine promotes breast cancer metastasis through a ubiquitin-specific peptidase 22-mediated lipolysis circuit."
39151008