Other Services

This Service

A database built with INDRA combining content from numerous readers and databases. This page allows you to curate the loaded statements. For more information please see the manual.

This Project

INDRA is developed by indralabs, a part of the Harvard Medical School Laboratory of Systems Pharmacology.

This project, indra_db, is also developed by the indralab team. For more information on how we procure our sources, you can go here. This work was funded by ARO grant W911NF‐15‐1‐0544 under the DARPA Communicating with Computers program.

IndraLab

Statements

RAF binds RAS, SOS, EGFR, and GRB2. 2 / 2

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sparser

"The EGFR interacts with adaptor proteins Grb2 and SOS, activating Ras and Raf, followed by phosphorylation of Mitogen-activated protein kinase/ERK and extracellular signal–regulated kinase (ERK)."

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➶

sparser

"Overexpression and/or mutant forms of EGFR, GRB-2, SOS, RAS and RAF are reported to cause oncogenic transformation (Bi- shop, 1991; McCormick, 1993; Cuadrado et al., 1993; Egan and Weinberg, 199[MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"

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Our Sources:

INDRA allows us to combine the results from a multitude of sources. In particular, the INDRA Database draws on the following...