IndraLab

Statements

FUS inhibits PAN2. 3 / 3
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"The authors have shown FUS to be normally present in a complex with three 3′-end processing factors (CPSF6, PAN2, PABPC1); while FUS normally sequesters PAN2, and prevents it from deadenylating Gria1 [MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"
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"These data suggest that FUS might sequester PAN2 on the PABP from attacking the poly (A) tail."
25968143
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"These data suggest that FUS sequesters PAN2 on PABPC1 and prevents it from deadenylating the poly (A) tail of the bound mRNA (XREF_SUPPLEMENTARY)."
25968143