IndraLab

Statements

USP12 deubiquitinates PHLPP1. 8 / 9
1 | 8
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"Secondly, Usp12 deubiquitinates and stabilises PHLPP and PHLPPL proteins which enhances dephosphorylation and deactivation of Akt."
25216524
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"It is possible that USP12 may deubiquitinate and stabilize PHLPP only at higher cellular levels of USP12."
28063927
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"The UAF1/USP12 complex deubiquitinates PHLPP1 and suppresses the proliferation of tumor cells (41)."
36988464
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"Usp12 deubiquitinates and stabilises PHLPP and PHLPPL and controls Akt activation status."
25216524
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"The deubiquitinating enzyme Usp12 deubiquitinates and stabilizes PHLPP and PHLPPL."
26525204
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"Further analysis using denaturing immunoprecipitation experiments revealed that Usp12 can also deubiquitinate and stabilise both PHLPP and PHLPPL."
25216524
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"USP12 deubiquitinates AKT phosphatase PHLPP."
38275816
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"USP12-Uaf-1-WDR20 complex directly deubiquitinates and stabilizes PHLPP and PHLPPL, resulting in a decrease in the active p-Akt level."
37752518