IndraLab

Statements


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"Thus, these data suggested that UCHL1 may promote osteosarcoma cell survival and reduces apoptosis by activating both Akt and MAPK/ERK pathways.Next, we determined whether knockdown of UCHL1 in osteos[MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"

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"In addition, UCHL1 overexpression enhanced cell viability and promoted oxidative damage, apoptosis and senescence in H 2 O 2 -induced HEI-OC1 cells."

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"UCH-L1 is highly expressed in neurons and has been demonstrated to promote cell viability and maintain neuronal integrity."

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"UCHL1 enhanced cell survival by reducing apoptosis."

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"UCH-L1 supports cell survival in H838 cells."

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"UCH-L1 is highly expressed in neurons and has been shown to promote cell viability and maintain neuronal integrity."

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"In conclusion, UCHL1 was confirmed to increase cell viability and proliferation as well as metastasis potential by stabilizing HIF‐1α to increase HIF‐1 activity in the spheroid 3D culture system.4 DISCUSSION."