IndraLab

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MYSM1 activates BLNK. 3 / 3
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"MYSM1 depletion suppresses cell proliferation and increases antiestrogen sensitivity in BCa-derived cell lines."

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"MYSM1 depletion attenuates BCa-derived cell growth in xenograft models and increases the sensitivity of antiestrogen agents in BCa cells."

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"Above all, the results indicate that MYSM1 promotes cell proliferation and G1-S phase transition in BCa, and the effect of MYSM1 on cell growth is partially related to ERα pathway.To test the functional of MYSM1 on BCa cell growth in vivo, MCF-7 cells infected with shMYSM1 or negative control lentivirus (shCtrl) were individually implanted subcutaneously into flank sides of 4-week-old female BALB/c nude mice (n = 7) armpit."