IndraLab

Statements


USP41 leads to the ubiquitination of SNAI1. 3 / 3
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"Moreover, siRNA-mediated USP41 downregulation increased the ubiquitination of Snail in both breast cancer cells (Figure 5B), whereas overexpression of USP41 decreased Snail ubiquitination (Figure 5C)."

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"Collectively, these results suggest that Snail ubiquitination is modulated by the expression levels of USP41 and TRIM21."

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"Therefore, we supposed that the balance of USP41 and TRIM21 may modulate the ubiquitination and stabilization of Snail."