IndraLab

Statements


OTUB1 activates MAF. 4 / 4
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eidos
"Inhibition of Otub1 results in c-Maf degradation and MM cell apoptosis18 ."

reach
"Consistently, silence of Otub1 promotes the degradation of c-Maf and MM cell apoptosis."

eidos
"Because Otub1 is a deubiquitinase of c-Maf and inhibition of Otub1 leads to c-Maf degradation and MM cell death ."

reach
"Consistent with this finding, overexpression of Otub1 increased c-Maf transcriptional activity, but it was decreased by AVT in a dose dependent manner."