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This Service

A database built with INDRA combining content from numerous readers and databases. This page allows you to curate the loaded statements. For more information please see the manual.

This Project

INDRA is developed by indralabs, a part of the Harvard Medical School Laboratory of Systems Pharmacology.

This project, indra_db, is also developed by the indralab team. For more information on how we procure our sources, you can go here. This work was funded by ARO grant W911NF‐15‐1‐0544 under the DARPA Communicating with Computers program.

IndraLab

Statements

OTUB1 activates MAF. 3 / 3

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"Consistent with this finding, overexpression of Otub1 increased c-Maf transcriptional activity, but it was decreased by AVT in a dose dependent manner."

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"Inhibition of Otub1 results in c-Maf degradation and MM cell apoptosis18 ."

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"Because Otub1 is a deubiquitinase of c-Maf and inhibition of Otub1 leads to c-Maf degradation and MM cell death ."

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Our Sources:

INDRA allows us to combine the results from a multitude of sources. In particular, the INDRA Database draws on the following...