IndraLab

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OTUB1 activates MAF. 3 / 3

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"Consistent with this finding, overexpression of Otub1 increased c-Maf transcriptional activity, but it was decreased by AVT in a dose dependent manner."

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"Inhibition of Otub1 results in c-Maf degradation and MM cell apoptosis18 ."

32999280

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eidos

"Because Otub1 is a deubiquitinase of c-Maf and inhibition of Otub1 leads to c-Maf degradation and MM cell death ."

32999280

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IndraLab

Statements

OTUB1 activates MAF. 3 / 3

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