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USP2 activates ATP. 3 / 3

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"Since the OCR is mainly determined by OXPHOS , USP2 deficiency seems to inhibit ATP synthesis in the mitochondria of cultured myoblasts ."

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"Mechanistically, an ML364 treatment experiment suggests that USP2 inhibits the accumulation of ROS in VMH neurons, and thereby leads to continued ATP production in the mitochondria."

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"In myoblasts, USP2 knockout decreased the accumulation of intracellular ATP and oxygen consumption."

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IndraLab

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USP2 activates ATP. 3 / 3

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