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EGF inhibits USP8. 2 / 2

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"In EGFR-ErbB2 expressing cells, EGF induced Usp8 tyrosine phosphorylation was even lower in the presence of PD153035 than the Usp8 tyrosine phosphorylation level observed in unstimulated and mock trea[MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"

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"In cells expressing either EGFR or EGFR-ErbB2, removal of the MIT domain (Usp8 Delta140) resulted in a decrease of the EGF induced Usp8 tyrosine phosphorylation, when compared to Usp8 wt."

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EGF inhibits USP8. 2 / 2

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