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OTUD1 decreases the amount of Reactive Oxygen Species. 2 / 2
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"As expected, OTUD1 reduced apoptosis rate, enhanced MMP and attenuated ROS levels in AML12 under H/R conditions (Figs."

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"Therefore, OTUD1 may antagonize these E3s.In the presence of excess amounts of ROS, KEAP1 induces cell death named oxeiptosis through binding with PGAM5 and AIFM1 [25]."