IndraLab

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UCHL3 activates Melanoma. 2 / 2
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"Taken together, the results of the present study suggest that UCHL3 knockdown decreases melanoma cell proliferation by increasing cell autophagy through regulating NEDD8 expression and autophagosome numbers."
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"Furthermore, autophagy was significantly enhanced along with the decrease in NEDD8 ubiquitination.In conclusion, the results of the present study demonstrated that UCHL3 knockdown decreased melanoma cell proliferation by increasing cell autophagy through regulating NEDD8 expression and autophagosome numbers in vitro."
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