IndraLab

Statements

UCHL5 activates proteolysis. 3 / 3
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"RNAi of both Uch37 and Usp14 also had no effect on proteasome structure or proteolytic capacity, but inhibited cellular protein degradation."
18162577
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"The RNAi of UCHL5 or USP14 alone does not affect cell growth and proteasome composition but accelerates cellular protein degradation; however, RNAi of both UCHL5 and USP14 can inhibit cellular protein degradation."
26097878
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"It has been shown that UCHL5 controls proteasome function and inhibition of UCHL5 promotes protein degradation in autophagy XREF_BIBR."
27604640