IndraLab

Statements


USP11 deubiquitinates Nucleoproteins. 3 / 3
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"The result showed that both USP10 and USP11 specifically co-precipitated with NP-HA (lanes 1, 3 and 4, lower panel), consistent with the published result, and NP could be deubiquitinated by only USP11 but not USP10 (lanes 3 and 4, upper panel)."

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"(B) Deubiquitination of NP by cellular USP11 may lower its binding affinity to cRNA."

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"These results combined suggest that USP11 inhibits viral RNA replication through deubiquitinating NP."