IndraLab

Statements


NFE2L1 increases the amount of USP7. 2 / 2
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"Expression of wildtype USP7, but not its catalytically defective mutant, resulted in decreased ubiquitination of TCF11 and Nrf1a, leading to their increased stability and increased transactivation of reporter gene expression by TCF11 and Nrf1a."

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"Overexpression of wildtype, but not mutant, USP7 enhanced transactivation by TCF11 and Nrf1a in a luciferase reporter assay."