IndraLab

Statements


SOX2 increases the amount of USP22. 3 / 3
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"USP22 is located directly on the Sox2 promoter and negatively regulates Sox2 transcription in ESCs [XREF_BIBR]."

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"USP22 is known to bind to the promoter region of Sox2 and negatively regulates Sox2 transcription in embryonic stem cells (ESCs) 47."

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"USP22 has been found to be located directly on the Sox2 promoter and catalyzes deubiquitination of H2B and attenuates Sox2 transcription."