IndraLab
Statements
5-(tetradecyloxy)-2-furoic acid inhibits JAK1. 1 / 1
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"The kinase inhibitor Tofacitinib (Tofa), a small molecule that preferentially blocks JAK1 activity, was administered in a clinically relevant regimen to mimic the human exposure, at doses that largely block phospho-Stat1 activation by IFN, alone or prior to a 2-hr parenteral IFN challenge."