IndraLab

Statements

Chromium atom decreases the amount of IRS1. 7 / 7
| 7
reach
"Various doses of chromium malate, chromium trichloride and chromium picolinate significantly reduced the mRNA expressions of GLUT-4 and Irs-1 when compared to normal control group (p < 0.05)."
35521592
reach
"Chromium malate could enhance the levels of Irs-1, PPARγ, PI3K and p38-MAPK, and reduce p-Irs-1 and p-Irs-1/Irs-1 levels in 3T3-L1 adipocytes with insulin resistance."
35521592
reach
"Compared with the model group, chromium malate could significantly promote the expression levels of GLUT-4, Akt, Irs-1, PPARgamma, PI3K and p38-MAPK and their mRNA, increase p-AKT/AKT level, AKT and AMPKbeta1 phosphorylation and reduce Irs-1 phosphorylation and p-Irs-1/Irs-1 level in 3T3-L1 adipocytes (p < 0.05)."
35521592
reach
"Compared with model group, chromium malate could significantly promote the secretion levels of GLUT-4, Akt, Irs-1, PPARgamma, PI3K and p38-MAPK, promote AMPKbeta1 phosphorylation, and reduced the level of p-Irs-1 in L6 cells with insulin resistance."
30014353
reach
"Chromium glycinate, acetate and propionate decreased the amount of IRS-1 phosphorylated at serine."
21472246
reach
"Chromium malate could induce 3T3-L1 adipocytes with insulin resistance to express GLUT-4, Akt, Irs-1, PPARγ, PI3K and p38-MAPK proteins and mRNA, increase AMPKβ1 phosphorylation and p-AKT/AKT level and reduce Irs-1 phosphorylation and p-Irs-1/Irs-1 level."
35521592
reach
"Chromium glycinate, acetate, and propionate decreased the amount of IRS-1 phosphorylated at serine."
21243441