IndraLab

Statements

Nefazodone inhibits KCNH2. 8 / 8
4 | 4
ctd
No evidence text available
24374264
reach
"Nefazodone inhibited hERG channel activity in our system."
24374264
ctd
No evidence text available
26821276
ctd
No evidence text available
24052561
ctd
No evidence text available
28551711
reach
"A novel assessment of nefazodone induced hERG inhibition by electrophysiological and stereochemical method."
24374264
reach
"Nefazodone inhibited the hERG channel in a concentration dependent manner with an IC50 of 45.3 nM in HEK-293 cells."
24374264
reach
"However, nefazodone induced hERG inhibition indicated only a theoretical risk of cardiotoxicity."
24374264