IndraLab

Statements

TNF increases the amount of UCHL1. 5 / 7
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"Taken together, we demonstrate that TNFalpha upregulates UCH-L1 protein expression by enhancing UCH-L1 translation rather than inhibiting its degradation in VSMCs."
19945429
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"While TNFalpha dramatically enhanced UCH-L1 protein expression in vehicle treated RASMCs over-expressed with UCH-L1, it could not up-regulate UCH-L1 protein expression in cycloheximide treated cells (XREF_FIG)."
19945429
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"Presumably, TNFalpha is able to up-regulate UCH-L1 protein levels in RASMCs that UCH-L1 gene translation is blocked by cycloheximine if TNFalpha inhibits UCH-L1 degradation."
19945429
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"These results suggest that TNFalpha up-regulates UCH-L1 protein levels by inhibiting UCH-L1 degradation and/or increasing UCH-L1 translation."
19945429
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"However, Western blot analysis with a long time exposure revealed that TNFalpha stimulation slightly increased UCH-L1 protein expression (XREF_FIG)."
19945429