IndraLab

Statements

USP2 binds USP7. 5 / 5
| 2 3
sparser
"Eleven of these water molecules are found at identical positions in the USP2 and USP7 complexes ( xref F)."
16905103
reach
"Indeed, the 76 ubiquitin Cα positions of the USP2 and USP7 complexes differ with an rmsd of only 0."
16905103
sparser
"It is possible that upon mutating Leu8 to Ala in Ub, the absence of the hydrophobic interaction shifts the conformation of the β1–β2 loop in Ub and reduced its binding to USP7 and USP2."
27501351
sparser
"Indeed, the 76 ubiquitin Cα positions of the USP2 and USP7 complexes differ with an rmsd of only 0.74 Å. This high structural similarity shows that the different protocols for the preparation of USP/ubiquitin complexes have no influence on the overall ubiquitin binding mode."
16905103
reach
"Eleven of these water molecules are found at identical positions in the USP2 and USP7 complexes (Figure 2F)."
16905103