IndraLab

Statements

P47 binds VCPIP1. 5 / 5
| 5
sparser
"The inhibition of p97 ATPase activity can be reduced if both p47-binding sites are not occupied, and the metastable complex of VCIP135/p97/p47 would represent such a case: VCIP135 interacts with the p97/p47 complex that uses only one p47-binding site."
12473691
sparser
"Several lines of recent evidence suggest that ubiquitination may be implicated in the p97/p47 pathway; p47 binds to monoubiquitinated proteins and VCIP135 shows a deubiquitinating activity in vitro."
15749824
sparser
"As ATPases, NSF and p97 have specific co-factors: NSF-mediated fusion requires the proteins SNAPs and p115, while the p97-mediated pathway requires formation of a complex with p47 and VCIP135, or with p37 (Kondo et al., xref ; Uchiyama et al., xref )."
26734607
sparser
"However, it was proposed that the DUB VCIP135 forms an unstable ternary complex with p97 p47 during post-mitotic Golgi reassembly, where p47 would be associated with p97 via only one of its two bindin[MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"
26320413
sparser
"VCIP135 cannot interact with p47 directly ( xref A)."
12473691