IndraLab

Statements



reach
"Thus, the conclusion we derived from this study is that USP37 downregulation does decrease the proliferation rate of the cells and this transient effect of USP37 could be successfully captured by the 3D cell culture model.4."

reach
"Since concomitant loss of REST and USP37 expression attenuated p27 stabilization and differentiation and rescued cell proliferation, our data strongly suggest that repression of USP37 and consequent p27 degradation, are important for REST dependent maintenance of cell proliferation."

eidos
"Functionally , downregulated USP37 decreases cell proliferation and anchorage-independent growth [ 28 ] ."
| PMC

reach
"These findings indicate that ectopic USP37 not only blocked REST dependent cell proliferation, but also countered the blockade to neuronal differentiation even in the presence of REST."

reach
"Functionally, USP37 depletion causes decreased cell proliferation measured by MTS, two-dimensional (2D) colony formation as well as three-dimensional (3D) anchorage- independent growth."

reach
"Functionally, downregulated USP37 decreases cell proliferation and anchorage-independent growth [28]."
| PMC