IndraLab

Statements


USP21 inhibits NFE2L2. 3 / 3
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"Collectively, these results demonstrate that USP16 directly interacts with KEAP1 to prevent the activation of Nrf2 signaling."

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"Overexpression of USP16 completely abrogated activation of the Nrf2 signaling pathway by FGF18 treatment and its antiapoptotic effects, while overexpression of the USP16 mutant (C205S) did not (Fig. 6G)."

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"USP16 directly interacts with KEAP1 and prevents the activation of Nrf2 signaling."