IndraLab

Statements

SAIT301 inhibits USP8. 2 / 2

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"This result suggests that SAIT301 perturbs USP8 mediated modulation of LRIG1, resulting in the degradation of LRIG1."

24828152

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"These results support the hypothesis that the presence of USP8 may affect the potency of anti-tumor efficacy of SAIT301, and SAIT301 may benefit from concomitant inhibition of USP8 for improved efficacy."

24828152

INDRA sources:

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IndraLab

Statements

SAIT301 inhibits USP8. 2 / 2

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