IndraLab

Statements


ITGAM increases the amount of CD44. 2 / 2
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"We found that CD44 in 4-month-old mice was highly expressed by all CD11b + CD45 high but not CD11b + CD45 low CNS MPs in WT and 5xFAD mice, suggesting that CD11b + CD45 high CNS MPs may be of peripheral origin but it still remains possible that CD44 expression is upregulated by microglia with aging and in inflammatory states."

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"We also found that CD44, recently suggested as a marker of peripherally derived CNS infiltrating immune cells in mice, was highly expressed by CD11b + CD45 high CNS MPs but not by CD45 low CNS MPs in both WT and 5xFAD mice."