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Metoclopramide inhibits KCNH2. 2 / 2

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"Both domperidone and metoclopramide concentration-dependently blocked HERG currents, and the following values were calculated for IC (50) (the concentrations causing half-maximal inhibition) and n (the Hill coefficient) : 57.0 nmol/l and 0.99 for domperidone, 5.4 micromol/l and 0.95 for metoclopramide."

15640612

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15640612

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Metoclopramide inhibits KCNH2. 2 / 2

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