IndraLab

Statements

USP25 activates Alzheimer Disease. 3 / 3

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"Genetic deletion of Usp25 reverses cognitive and synaptic deficits in AD mice."

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"Zheng et al found that USP25 promoted AD by potentiating microglia-mediated neuroinflammation [23] ."

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"Besides, we have found that USP25 can also promote AD by enhancing Aβ generation through inhibiting the ubiquitination and lysosomal degradation of APP and BACE1 [39] ."

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INDRA sources:

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IndraLab

Statements

USP25 activates Alzheimer Disease. 3 / 3

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