IndraLab

Statements

reach
"Comparable to other hERG antagonists [11,15,16] , EGCG inhibited hERG currents preferably in the open and in the inactivated states, but not in the closed states."
17961513
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"Overall, electrophysiological properties of hERG inhibition by EGCG are comparable to those of several already characterized pharmaceutical compounds such as the antidepressant trazodone, the antiarrh[MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"
17961513
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"Similar to (±)-naringenin, epigallocatechin gallate, the main flavonoid found in green tea, inhibits hERG channels only in the open and inactivated state both in HEK293 cells (IC 50 6 μM) and in Xenop[MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"
33727059
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"EGCG inhibited hERG in a dose-dependent manner."
17961513
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"In this study, we have provided the first investigation of the effects of EGCG on cloned hERG channels, demonstrating that EGCG is a low-affinity inhibitor of hERG with electrophysiological properties[MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"
17961513